Summary: Of key importance to the pharma industry, this book looks at the contribution of the range of new and innovative tools used for preformulation and formulation of medicines which help to optimize pharmaceutical development projects. Such tools also assist with the performance evaluation of the pharmaceutical process which has already been implemented and which is currently being commercialized - thereby allowing any potential gaps to be identified. This information can also be used to perform optimization of processes. These tools can be applied in both basic research and industrial environment. The tools described in this book also permits the evaluation of the proposed formulation which provides data for a better understanding of the process and the product which supports the development of medicines according to recent new strategies of 'Quality by Design' and 'New Strategy for Process Validation Guidelines'. The tools included in this book are: expert systems; artificial intelligence tools, neuro-fuzzy tools, multimedia tools, artificial neural networks, neurofuzzylogic and genetic programming, plus other mathematical tools. This book is extremely topical since the regulatory environment is changing (such as the ICH (International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use) and the New Guidance of Process Validation - and the use of preformulation tools in the pharmaceutical industry will help in the development of medicines according to Quality by Design and GMP with 21st century principles.