This book comprehensively covers the mechanisms of action and inhibitor design for HIV–1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Despite numerous review articles and isolated book chapters dealing with HIV–1 integrase, there has not been a single source for those working to devise anti–AIDS drugs against this promising target. But this book fills that gap and offers a valuable introduction to the field for the interdisciplinary scientists who will need to work together to design drugs that target HIV–1 integrase.

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