Many components of current novel therapeutic modalities for Hepatocellular carcinoma (HCC) are discussed in the book within the framework of a multidisciplinary approach with special emphasis on emerging treatment approaches and research strategies. This book is the essential clinical guide for oncologists, hepatologists, surgeons, and all physicians and researchers involved in the care of patients with HCC.

Contents
Preface
1 Role of Alleles and Genotypes of Polymorphisms of IL-18 (-607 C/A; and -137 C/G), IFN-γ (+874 A/T) and TNF-α (-238 A/G and -308 A/G) and HLA-G Genes in the Susceptibility of Hepatocellular Carcinoma
2 Liver Transplantation for Hepatocellular Carcinoma
3 Radioembolization for the Treatment of Unresectable Hepatocellular Carcinoma
4 Image-Guided Therapies for Hepatocellular Carcinoma in Hepatocelluar Carcinoma — Future Outlook
5 Neoadjuvant Chemotherapy for Hepatocellular Carcinoma
6 Targets and Approaches to Control Hepatocellular Carcinoma in Future
7 Early Chronic Inflammation and Subsequent Somatic Mutations Shift Phospho-Smad3 Signaling from Tumor-Suppression to Fibro-Carcinogenesis in Human Chronic Liver Diseases
8 Surgical Treatment Strategies and Prognosis of Hepatocellular Carcinoma
9 Conditions that Predispose to the Development of HCC: The Role of Tumor Associated Fibroblasts and of microRNA
10 Signs and Symptoms
11 Sorafenib in the Continuum of Care for Hepatocellular Carcinoma: Challenges in Defining Optimal Practice
12 Sorafenib-lnhibited Signaling: Emerging Evidence of RAF-lndependent Pathways as Potential Therapeutic Targets in Hepatocellular Carcinoma
13 Insulin-Like Growth Factor-ll: Molecular-Targeted Therapy for Hepatocellular Carcinoma
14 Simultaneous Changes in Expression of Bile Canalicular CD10 and Sinusoidal CD105 (Endoglin) in Chronic Hepatitis and Liver Cirrhosis
15 Hepatocellular Carcinoma, Steroid Hormones and Metalloproteases

Download File Size:8.58 MB

---