The incidence of endometrial cancer is increasing – particularly in industrialized countries – thought to be due to a combination of factors including hormonal imbalance (hyperestrinism), obesity and aging of the population. In contrast to the cervix, where cytologic screening has been enormously successful in preventing cervical cancer, there is no effective general population screening of asymptomatic women for endometrial cancer.

Most endometrial adenocarcinomas present with symptoms of postmenopausal bleeding triggering evaluation of the uterine cavity. A variety of collection techniques are available to obtain cytologic or histopathologic samples for diagnosis. However, interpretation of such specimens can be difficult without proper collection and preparation. Thankfully, this monograph provides a most valuable educational resource for the pathologist and cytopathologist in the techniques of endometrial sampling and diagnosis.

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