The book contains over 350 chapters of comprehensive coverage on cell signaling. It includes discussion on topics from ligand/receptor interactions to organ/organism responses, and provides user-friendly, well-illustrated, reputable content by experts in the field. "Handbook of Cell Signaling, Three-Volume Set, 2e", is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. "Handbook of Cell Signaling, 2/e" will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors.