This book provides a historical perspective of graft-vs-host disease as well as the discussion of the mechanisms involved in graft-vs-host disease. Understanding the mechanisms of graft-vs-host disease will allow for the development of better preventative and therapeutic measures. This field continues to be an area of active research as we understand better and better how T-cells become activated and the important factors associated with activated T-cells such as specific cytokines released or specific cytokines which may effect T-cell functions. These particular aspects are covered in this book as well as a discussion on the potential therapies and prophylactic regimens associated with graft-vs-host disease.

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