The special volume “Biosystems Engineering” reflects an emerging field of applied research that aims at a system-level understanding of biological systems toward their targeted design and improvement. To obtain system-wide insight, interdisci-plinary approaches are applied, which integrate expertise from biologists, engi-neers, and computer scientists, who have developed powerful analytical methods, modelling concepts, and information technologies for this challenging task. With the increasing need for sustainable production of fuels and chemicals from renew-able resources, a major focus in this area is on the optimization of biotechnological production strains and processes. Of specific importance hereby is the consideration of the microorganism as a part of the bioprocess in its entirety.

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