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"Advances in the Molecular Understanding of Colorectal Cancer" ed. by Eva Segelov
ITExLi | 2019 | ISBN: 1789850606 9781789850604 1789850592 9781789850598 | 155 pages | PDF | 7 MB
This book covers the major areas of importance in the field, incorporating new knowledge that has arisen due to the advancement of molecular techniques and the ability to correlate molecular changes with clinical behaviour of tumours.
An understanding of the molecular pathogenesis of colorectal cancer by researchers and clinicians is essential to facilitate progress in improving patient outcomes in this common cancer that still carries a poor prognosis if not identified early.
Each chapter is a summary written by experts, concisely summarising current data as well as highlighting potential areas for advancement. Appreciating the differences between tumours on a molecular level is the key to developing and delivering precision medicine, and nowhere is this more critically required than in the field of colorectal cancer.
Contents
1 Advances in Molecular Subclassification of Colorectal Cancer
2 Experimental Results Help Shape the Development of Personalized Medicine in Colorectal Cancer
3 BRAF Mutation in Colorectal Cancer
4 Current Utility and Future Applications of ctDNA in Colorectal Cancer
5 Epigenetic Biomarkers and Their Therapeutic Applications in Colorectal Cancer
6 Predictive Biomarkers for Monoclonal Antibody Therapies Targeting EGFR (Cetuximab, Panitumumab) in the Treatment of Metastatic Colorectal Cancer
7 Finding Needles in Haystacks: The Use of Quantitative Proteomics for the Early Detection of Colorectal Cancer
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