A comprehensive look at the latest research findings and clinical applications
of oncogenic viruses
Written by a panel of academic experts, Viral Oncology is the first self-contained and
comprehensive book to present both scientific and clinical information on viruses linked
to some of the most important human cancers. Readers can turn to this book for the most
in-depth and up-to-date coverage of: HPV-associated cancers; molecular events associated
with HPV-induced human cancer; the role of the HPV E6 oncoprotein in malignant progression;
virus association with brain tumors; involvement of the polyomavirus JCV in colorectal
cancer; possibleassociation of BKV with prostate cancer; oncogenic transformation
bypolyomavirus large T antigen; SV40 and human cancer; SV40 and mesothelioma; molecular
immunology of hepatitis B.associated viral cancer; hepatitis B vaccine and hepatocellular
carcinoma; pathogenesis of acute and chronic hepatitis Cvirus infection; molecular mechanisms
of hepatitis C virus-induced cellulartransformation; clinical aspects of HTLV-1 associated
cancer; oncogenic potential of the HTLV-1 tax protein; HIV-associated malignancy; HIV-
related lymphoma; biology and epidemiology of HHV-8; the role of KSHV in pathogenesis of
Kaposi'ssarcoma; molecular pathobiology of EBV infection; and EBV as a pathogen.
Several chapters are devoted to the basic science of oncogenic viruses for thestudy of
their pathogenesis, drug development, and employment of viral vectorsfor vaccine and gene
therapy. The book also includes complementary clinically based chapters describing natural
courses and treatments. Additionally, bonusclinical materials are embedded within chapters
and an easy-to-use indexcompletes the book.
Viral Oncology is an essential resource for clinical and research oncologists in medical
facilities and biological research laboratories; clinicians and scientists working in
related biomedical areas; medical students working toward a first or higher degree in the
life sciences and other biomedical fields; and pharmaceutical scientists and developers
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