Chromosomal Instability and Aging: Basic Science and Clinical Implications by Fuki Hisama, Sherman M. Weissman and George M. Martin
English | 1 edition | February 2003 | ISBN-10: 0824708563 | 600 pages | PDF | 5,2 Mb
This text examines the relationship between DNA damage and repair, cellular senescence, genomic instability and ageing. It includes in-depth discussions of various types of DNA damage, the DNA repair network, and cellular responses to genetic damage to assess their impact on the modulation of ageing processes and age-related disease, including cancer development.
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