The latest edition of the authoritative reference to HPLC
High-performance liquid chromatography (HPLC) is today the leading technique
for chemical analysis and related applications, with an ability to separate,
analyze, and/or purify virtually any sample. Snyder and Kirkland's Introduction
to Modern Liquid Chromatography has long represented the premier reference to
HPLC. This Third Edition, with John Dolan as added coauthor, addresses important
improvements in columns and equipment, as well as major advances in our
understanding of HPLC separation, our ability to solve problems that were
troublesome in the past, and the application of HPLC for new kinds of samples.
This carefully considered Third Edition maintains the strengths of the previous
edition while significantly modifying its organization in light of recent research
and experience. The text begins by introducing the reader to HPLC, its use in
relation to other modern separation techniques, and its history, then leads into
such specific topics as:
The basis of HPLC separation and the general effects of different experimental
conditions
Equipment and detection
The column.the "heart" of the HPLC system
Reversed-phase separation, normal-phase chromatography, gradient elution, two-
dimensional separation, and other techniques
Computer simulation, qualitative and quantitative analysis, and method validation
and quality control
The separation of large molecules, including both biological and synthetic
polymers Chiral separations, preparative separations, and sample preparation
Systematic development of HPLC separations.new to this edition
Troubleshooting tricks, techniques, and case studies for both equipment and
chromatograms
Designed to fulfill the needs of the full range of HPLC users, from novices to
experts, Introduction to Modern Liquid Chromatography, Third Edition offers the
most up-to-date, comprehensive, and accessible survey of HPLC methods and
applications available.
http://www.amazon.com/Introduction-Modern-Liquid-Chromatography-Snyder/dp/0470167548
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